Thiazide and thiazide-like agents
Web11 Aug 2012 · Thiazide and thiazide-like diuretics have been widely used as blood pressure-lowering agents for more than 5 decades. However, their use in patients with advanced chronic kidney disease has been limited and often discouraged. The exact mechanism of how thiazide and thiazide-like diuretics lower blood pressures is still in question. WebBackground: Photosensitizing diuretics use (especially thiazide compounds) is associated with a significantly higher risk of squamous cell carcinoma (SCC). Actinic keratosis (AK) is a precursor of SCC. Study aim: To evaluate in a prospective cohort study the efficacy of topical piroxicam 0.8% and sunscreen 50+ (ACTX) in the treatment of AK in ...
Thiazide and thiazide-like agents
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WebOur analysis made a comprehensive comparison of thiazide-type and thiazide-like diuretics to indicate that to achieve the same level of BP reduction, thiazide-like diuretics were not … Web11 Mar 2015 · This article will focus on the available evidence pertaining to HCTZ versus CTD and IDP, and will review the pharmacological differences between these three diuretics, as well as the clinical trial data and important side effects. Thiazide and thiazide-like diuretics are cornerstone treatments for hypertension. However, unlike chlorthalidone …
Web18 Oct 2024 · After their initial discovery, thiazides and thiazide-like diuretics rapidly became first-line agents for the treatment of hypertension through their natriuretic and vasodilating properties. More importantly, beyond their efficacy as antihypertensive drugs, thiazides have been shown to reduce hypertension-related morbidity and mortality [ 4 ]. Web14 Apr 2024 · Thiazide and thiazide-like diuretics are first-line antihypertensive agents that lower blood pressure and prevent adverse cardiovascular outcomes. ... These data support that the 6- and 7-position groups are essential for diuretic activity of thiazide and thiazide-like drugs such as chlorthalidone, which showed similar effects and long-term ...
Web31 Aug 2024 · Thiazide-type diuretics include bendroflumethiazide (BDTZ) and hydrochlorothiazide (HCTZ) while other drugs with a similar pharmacological action but a different chemical structure, such as indapamide (INDA) and chlorthalidone (CLTD), are termed thiazide-like diuretics. Thiazide-type diuretics achieve their diuretic action via … Web14 Jun 2024 · The pharmacological interaction of thiazide diuretics with drugs such as lithium, angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, antidiabetic, and Vitamin D...
Web31 Aug 2024 · Thiazide-type diuretics include bendroflumethiazide (BDTZ) and hydrochlorothiazide (HCTZ) while other drugs with a similar pharmacological action but a …
WebThiazide and thiazide-like diuretics (chlorothiazide, hydrochlorothiazide, metolazone) inhibit reabsorption of sodium in distal tubules, causing increased excretion of sodium and … maschere del moliseWebThiazide-like diuretics should be prescribed with caution in the elderly and people with: Diabetes, gout, and systemic lupus erythematosus — due to risk of exacerbation of these conditions. Severe cardiovascular disease, or who are being treated with cardiac … dataverse mdlWeb5 Mar 2015 · Thiazide diuretics are recommended as first-line therapy for hypertension and are among the most commonly prescribed drugs worldwide. According to their molecular … maschere del piemonteWebThiazides are used to relieve oedema due to chronic heart failure and, in lower doses, to reduce blood pressure. Loop diuretics are used in pulmonary oedema due to left … dataverse merge duplicatesWebMost cases are caused by thiazide or thiazide-like agents; loop diuretics are implicated much less commonly. Thiazides may be the sole factor responsible for causing hyponatremia and they may also exacerbate hyponatremia in patients with disorders associated with SIADH (101, 184, 266). The mechanism of thiazide-induced hyponatremia … maschere della lombardiaWebThiazide diuretics are a type of diuretic (a drug that increases urine flow). They act directly on the kidneys and promote diuresis (urine flow) by inhibiting the sodium/chloride … maschere del teatro greco e romanoWebThiazide (benzothiadiazine) diuretics were originally developed more than 50 years ago as a result of chemical modification of sulfanilamide, a sulfonamide inhibitor of carbonic anhydrase. 1 Unlike inhibitors of carbonic anhydrase, however, thiazides were found to be associated with higher excretion of sodium and chloride with minimal loss of … maschere di animali da colorare e ritagliare