Ribophagy receptor
Webb23 mars 2024 · GSEA results show that these four genes are mainly involved in several neurodegenerative diseases (PD, AD, HD, long-term depression, and ALS), neural function related pathways (neurotrophic signaling pathway, axon guidance, neuroactive ligand receptor interactions, and glycosphingolipid biosynthesis ganglion series), metabolism … WebbAlthough ribophagy was demonstrated in budding yeast a decade ago, a specific receptor for this process has been unknown. Recently, a study revealed that NUFIP1 (nuclear …
Ribophagy receptor
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WebbMCE 引用文献：PMID: 25178155 DRAK2 emerged as a promising drug target for the treatment of autoimmune diseases and to prevent graft rejection after organ transplantation. Screening of a compound library in a DRAK2 binding assay led to the identification of an isothiazolo[5,4-b]pyridine derivative as a novel ligand for DRAK2, …
Webbför 2 dagar sedan · add_box. NEW YORK, April 12, 2024 (GLOBE NEWSWIRE) -- Cognition Therapeutics, Inc. (NASDAQ: CGTX) announced that a review article titled, “Sigma-2 Receptors – From Basic Biology to Therapeutic ... WebbCD4 + T lymphocytes play a major role in the establishment and maintenance of immunity. They are activated by antigenic peptides derived from extracellular or newly synthesized (endogenous) proteins presented by the MHC-II molecules. The pathways leading to endogenous MHC-II presentation remain poorly characterized. We demonstrate here that …
WebbRibophagy. Ribophagy (ribosomes, 20–25 nm) [17] is a selective autophagy process leading to ribosomal turnover, i.e., a large supply of amino acids and a protein translation … WebbMacroautophagy (hereafter called autophagy) is a highly conserved physiological process that degrades over-abundant or damaged organelles, large protein aggregates and …
Webb19 juli 2024 · NUFIP1 is a ribosome receptor for starvation-induced ribophagy. Science. 2024; 360: 751-758. Crossref; PubMed; Scopus (166) Google Scholar; showed that …
Webbphagy receptor for ribosomes (Figure 1, ‘‘selective’’). The LIR motif mutant, which is likely to be specifically defective in ribophagy, also allowed them to examine the physiological … team lillisWebb1 aug. 2024 · ABSTRACT. Although ribophagy was demonstrated in budding yeast a decade ago, a specific receptor for this process has been unknown. Recently, a study … team leisurelyWebbAutophagy: A brief overview in perspective of dermatology britska hudobna skupinaWebb2.3. NUFIP1 is the Ribophagy Receptor in Mammalian Cells Selective autophagy receptors recognize specific cargoes and also bind to the autophagic protein Atg8 (LC3 in … britse jeugdjournaalWebb9 apr. 2024 · Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase. Nature communications, 8 (2024), p. 743. View in Scopus Google Scholar [16] S. Ma, X. Zhang, L. Zheng, Z. Li, X. Zhao, W. Lai, et al. Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1 ... britska jidlaWebb22 nov. 2024 · This work investigated the effect of thyroxine on the biogenesis and quality control system in rat heart mitochondria. In hyperthyroid rats, the concentrations of free triiodothyronine and thyroxine increased severalfold, indicating the development of hyperthyroidism in these animals. The electron microscopy showed 58% of cardiac … teamleiter toomWebb7-Ketocholesterol and 5,6-secosterol are cholesterol autoxidation products generated under oxidative stress by two distinct mechanisms. They are present in atherosclerotic plaques and are candidate players in the disease initiation and progression. team lines hamburg