Neotanshinlactone
WebDec 14, 2015 · The genus of Salvia is a large pool of diterpenoids with structural diversity and biological properties [1–3].Many diterpenoids with interesting bioactivities, such as tanshinone IIA, salvicine, neotanshinlactone, and salvinorin A, have been reported from this genus [4–6].Salvia yunnanensis is a traditional Chinese herb used as the surrogate … WebNeo-tanshinlactone C17H12O3 CID 10264769 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ...
Neotanshinlactone
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WebMar 14, 2024 · Antitumor agents 269. Non-aromatic ring-A neotanshinlactone analog, TNO, as a new class of potent antitumor agents WebNov 4, 2004 · Neo-tanshinlactone (1) was isolated and synthesized for the first time and evaluated in vitro against several human cancer cell lines. Compound 1 showed significant inhibition against two ER+ human breast cancer cell lines and was 10-fold more potent and 20-fold more selective as compared to tamoxif …
WebNeo-tanshinlactone (1) was isolated and synthesized for the first time and evaluated in vitro against several human cancer cell lines. Compound 1 showed significant inhibition … WebFeb 11, 2010 · In studies by the authors' Natural Products Research Laboratories, neotanshinlactone (Figure 7), which has a lactone (NPRL) C-ring rather than an ortho-quinone, showed significant and selective ...
WebJun 20, 2024 · Several neo-tanshinlactone derivatives with fluorine or the trifluoromethyl group were synthesized and their antiproliferative activities were evaluated. Compared with neo-tanshinlactone, fluorinated derivatives showed a broad activity spectrum against human tumor lines. For a neo-tanshinlactone chemical skeleton, these results also … WebDec 1, 2010 · A small library of novel benzocoumarin derivatives based on naturally occurring neo-tanshinlactone scaffold was constructed and their antiproliferative activities …
WebSep 1, 2016 · Breast cancer, the most frequent cancer in women, is the second leading cause of cancer-related death. Estrogens and estrogen receptors are well recognized to …
WebDec 1, 2004 · Neotanshinlactone selectively inhibits the proliferation of estrogen receptor positive breast cancer cells through transcriptional down-regulation of estrogen receptor … kotak 811 account opening kycWebMar 23, 2010 · Request PDF On Mar 23, 2010, Yizhou Dong and others published ChemInform Abstract: Antitumor Agents. Part 269 Nonaromatic Ring-A Neotanshinlactone Analogue, TNO, as a New Class of Potent ... manny pacquiao greatest hitsWebOct 1, 2016 · Request PDF Neo-tanshinlactone D-Ring Modified Novel analogues Induce Apoptosis in Human Breast Cancer Cell via DNA Damage Neo-tanshinlactone (NTL) a … kotak 811 account close onlineWebApr 30, 2013 · A small library of novel benzocoumarin derivatives based on naturally occurring neo-tanshinlactone scaffold was constructed and their antiproliferative activities against breast cancer cells MCF-7 ... manny pacquiao first fight as a kidkotak 811 account apply onlineWebNov 15, 2009 · Tetrahydroneotanshinlactone (TNT) and tetrahydronaphthalene-1-ol (TNO) derivatives were designed, synthesized, and evaluated for cytotoxic activity. The TNO … manny pacquiao first beltWebDec 1, 2010 · Natural and synthetic coumarins have been found to exhibit a variety of pharmacological activities like anti-HIV, 9 anticoagulant, 10 antibacterial, 11 antioxidant, 12 and anti-inflammatory. 13 Among the diverse biological activities of coumarin the most intriguing bioactivity is the effect against breast cancer.14, 15, 16 Figure 1 shows the … manny pacquiao full fights