WebRats can also be trained to drink voluntarily from a syringe (see video below) and this approach has been shown to be both effective and to result in accurate dosing (Atcha et al, 2010 3). Material can also be dosed using a small flexible catheter introduced only into the animal’s mouth. WebFeb 1, 2011 · Intratracheal administration of tiotropium (0.6-6.4 nmol/kg) caused sustained (lasting at least 24 h) increase in the apparent dissociation constant (K(d)) for [(3)H]NMS binding in rat lung ...
The oral and intratracheal toxicities of ROUNDUP and its components to rats
WebDec 20, 2024 · We investigated the effects of intratracheal administration of autologous BMCs on MCT-induced pulmonary vessel remodeling and lung inflammation in rats. Methods All animal experiments were approved by the University of the Ryukyus Institutional Animal Care and Use Committee, and were performed in accordance with the National … WebPurpose. To evaluate the intratracheal route of administration as an alternative to oral administration for 2′,3′-dideoxyinosine (ddI). Methods. A ddI dose (40 mg/kg/300 µl or 6.5 mg/kg/50 µl) was instilled into the trachea in female Fisher rats and an intravenous tracer dose (9 µg/kg) of 3H-ddI was administered concomitantly to determine the drug … the weeknd type de musique
Intratracheal Instillation as an Exposure Technique for the …
WebJan 22, 2008 · After intratracheal administration of Man-7.5 and Man-5.0-liposomes in rats, a significantly high internalization and selective targeting to alveolar macrophages was observed. The enhanced cellular uptake in alveolar macrophages related to the mannose density of Man-liposomes was also confirmed both in vitro and in vivo confocal … WebNiO nanoparticles were administered to rat lungs via intratracheal instillation or inhalation. During pulmonary toxicity caused by NiO nanoparticles, the induction of oxidative stress … WebTo provide a toxicity test method which enables cheaply and simply evaluating the inhalation toxicity of chemicals, and a toxicity test kit. The toxicity test method in one embodiment involves a, b and c below. a: Calculate the use amount α of a test substance from the survival rate of the cells when the cells have been cultured using a culture fluid that … the weeknd uk