Externally, cantharidin is a potent vesicant (blistering agent), exposure to which can cause severe chemical burns. Properly dosed and applied, the same properties have also been used therapeutically, for instance, for treatment of skin conditions, such as molluscum contagiosum infection of the skin. See more Cantharidin is an odorless, colorless fatty substance of the terpenoid class, which is secreted by many species of blister beetles. It is a burn agent or a poison in large doses, but preparations containing it were historically used as See more Aphrodisiac preparations Preparations made from blistering beetles have been used since ancient times as an aphrodisiac, possibly because their physical effects were perceived to mimic those of sexual arousal, and because they can cause … See more General risks As a blister agent, cantharidin has the potential to cause adverse effects when used medically; for … See more • Dupuis, Gérard & Berland, Nicole (2004). "Cantharidin: Origin and synthesis," Lille, FR: Lycée Faidherbe, see [1], accessed 13 December 2015. See more Structure and nomenclature Cantharidin, from the Greek kantharis, for beetle, is an odorless, colorless natural product with … See more Poisoning by Epicauta species from cantharidin is a significant veterinary concern, especially in horses; species infesting feedstocks … See more Mechanism of action Topical cantharidin is absorbed by the lipid membranes of epidermal cells, causing the release of serine proteases, enzymes that break the peptide bonds in proteins. This causes the disintegration of desmosomal plaques, … See more WebMay 23, 2024 · Cantharidin is a defensive terpenoid found in blister beetles 1,2,3,4,5.Cantharidin has been investigated in many fields due to its powerful effects on treating tumors, pests control and ...
Zur Biosynthese des Cantharidins. I SpringerLink
WebOct 3, 2024 · Norcantharidin (NCTD) is the demethylated analog of cantharidin, with allegedly reduced toxicity. However, there is still limited information regarding its posology and potential risk in its use in cancer treatment. Healthy BDF1 mice were intraperitoneally administered with norcantharidin (0, 3, 6, 12, and 25 mg/kg) every 24 h for 6 days. … WebCantharidin C10H12O4 CID 5944 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... things to do in yardley pennsylvania
Characterization of Juvenile Hormone Related Genes Regulating
WebBACKGROUND Cantharidin (CTD) is one of the major active ingredients of blister beetles and has significant antitumor activity in many cancer cell lines. The aim of our study was to evaluate the effect of CTD on the apoptosis of human osteosarcoma WebSummary. In contrast to the female, the adult males of Lytta vesicatoria (Coleopt. Meloidae) produced radioactive cantharidine on injection with 14 C-1-acetate and 14 C-2 … WebApr 10, 2024 · Blister beetles are famous for its defensive compound, cantharidin, which is highly toxic to most animals (Dettner 1997, Ghaffarifar 2010, Khan et al. 2013).Cantharidin is a widely known insect defensive product or a sexual attractant and stimulates copulation in Epicauta nyassensis (Coleoptera: Meloidae) (Nikbakhtzadeh et al. 2007a, b,, 2012). ... things to do in yaroslavl